Resource
Porcine pancreas
Trypsin is a white or whitish crystalline powder. It is a proteolytic enzyme. It can selectively hydrolyze the peptide chain which is constructed of the carboxyl from lysine or arginine. It can digest the dissolved denatured protein but have not effect on the non-denatured proteins, so it can be used for decomposing and diluting pus, sputum and blood clots and then they can be easily removed to accelerate the cleaning of the wound surface and to promote the rebirth of the granulation tissue. It has the function of anti-inflammation.
Function
It is used for the treatment of local edema, hematoma and abscess caused by empyema, hemothorax, surgical inflammation, ulcers, traumatic injuries and fistula, or spray inhalation for respiratory diseases, and also treatment for injury by poisonous snake. It is also often used for treating tissues before the culture of animal cells.
Brief introduction of production
Trypsin is extracted and purified from porcine pancreas glands through a particular process.
Specifications (According to Pharmacopeia USP34
NF29 2011)
Items |
Company Specifications |
|
Characters |
White or almost white, crystalline powder |
|
Tests |
Solubility |
Conforms |
Loss on drying |
≤5.0% |
|
Residue on ignition |
≤2.5% |
|
Chymotrypsin |
≤5.0% |
|
Activity |
≥2500 USP U/mg (dried substance) |
|
Microbial Impurities |
TAMC |
≤103 cfu/g |
TYMC |
≤102 cfu/g |
|
Staphylococcus aureus |
Absence/g |
|
Pseudomonas aeruginosa |
Absence/g |
|
Escherichia coli |
Absence/g |
|
Salmonella |
Absence/10g |
Storage
Preserve in tight containers, and avoid exposure to excessive heat.
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